Travellers' diarrhoea--an insoluble problem.

Travellers' diarrhoea: slow but steady progress.

Membrane proteins: always an insoluble problem?

Membrane proteins play crucial roles in cellular processes and are often important pharmacological drug targets. The hydrophobic properties of these proteins make full structural and functional characterization challenging because of the need to use detergents or other solubilizing agents when extracting them from their native lipid membranes. To aid membrane protein research, new methodologies...

Sentinel surveillance for travellers' diarrhoea in primary care

BACKGROUND Travellers' diarrhoea is the most common health problem among international travellers and much of the burden falls on general practitioners. We assessed whether sentinel surveillance based in primary care could be used to monitor changes in the epidemiology of travellers' diarrhoea. METHODS A sentinel surveillance scheme of 30 volunteer general practices distributed throughout Wal...

Parasitic causes of prolonged diarrhoea in travellers - diagnosis and management.

BACKGROUND Prolonged infectious diarrhoea in the returning traveller is generally caused by protozoal and occasionally by helminth parasites. OBJECTIVE This article provides a framework for the diagnosis, management and prevention of the diseases that cause persistent diarrhoea in the traveller. DISCUSSION A large proportion of disease is caused by Giardia lamblia, Cryptosporidium parvum an...

Incidence, risk factors and treatment of diarrhoea among Dutch travellers: reasons not to routinely prescribe antibiotics

BACKGROUND Travellers' diarrhoea (TD) is the most common infectious disease among travellers. In the Netherlands, stand-by or prophylactic antibiotics are not routinely prescribed to travellers. This study prospectively assessed the incidence rate, risk factors, and treatment of TD among immunocompetent travellers. METHODS Persons who attended the travel clinic of the Public Health Service Am...